MyBioSource.com's Anti-Hu CD41/CD61 (PAC-1 epitope) PE is a Mouse monoclonal antibody. It reacts with Human. This antibody has been shown to work in applications such as: Cell Sorting, Isolation, Flow Cytometry, and Immunofluorescence.
Description
CD41 (platelet glycoprotein IIb, integrin alpha IIb) is composed of two subunits (120kDa transmembrane alpha chain and 23kDa extracellular beta chain) and interacts with CD61 (platelet glycoprotein IIIa, integrin beta 3) in the presence of calcium to form a Functional Application (FUNC)tional adhesive protein receptor. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin, and it is involved in platelet aggregation